Author: Christa Avampato

The short of it: Writer. Health, education, and art advocate. Theater and film producer. Visual artist. Product geek. Proud alumnae of the University of Pennsylvania (BA) and the Darden School of Business at the University of Virginia (MBA). Inspired by ancient wisdom & modern tech. Proliferator of goodness. Opener of doors. Friend to animals. Fan of creative work in all its wondrous forms. I use my business skills to create passion projects that build a better world. I’ve been called the happiest New Yorker, and I try hard to live up to that title every day. The long of it: My career has stretched across Capitol Hill, Broadway theatre, education, nonprofit fundraising, health and wellness, and Fortune 500 companies in retail, media, entertainment, technology, and financial services. I’ve been a product developer and product manager, theater manager, strategic consultant, marketer, voice over artist, , teacher, and fundraiser. I use my business and storytelling to support and sustain passion projects that build a better world. In every experience, I’ve used my sense of and respect for elegant design to develop meaningful products, services, programs, and events. While building a business career, I also built a strong portfolio as a journalist, novelist, freelance writer, interviewer, presenter, and public speaker. My writing has appeared in The Washington Post, The Huffington Post, PBS.org, Boston.com, Royal Media Partners publications, and The Motley Fool on a wide range of topics including business, technology, science, health, education, culture, and lifestyle. I have also been an invited speaker at SXSW, Teach for America, Avon headquarters, Games for Change, NYU, Columbia University, Hunter College, and the Alzheimer’s Foundation of America. The first book in my young adult book series, Emerson Page and Where the Light Enters, was acquired by a publisher and launched in November 2017. I’m currently working on the second book in the series. A recovering multi-tasker, I’m equally at home in front of my Mac, on my yoga mat, walking my rescue dog, Phineas, traveling with a purpose, or practicing the high-art of people watching. I also cut up small bits of paper and put them back together as a collage artist. My company: I’m bringing together all of my business and creative career paths as the Founder of Double or Nothing Media: • I craft products, programs, and projects that make a difference; • I build the business plans that make what I craft financially sustainable; • I tell the stories that matter about the people, places, and products that inspire me. Follow my adventures on Twitter at https://twitter.com/christanyc and Instagram at https://instagram.com/christarosenyc.
creativity

New research to relieve radiation fibrosis for cancer patients

Christa Avampato
Photo by Oksana Taran on Unsplash

Some nerdy science news! Ever since my early breast cancer diagnosis in 2020, I’ve participated in a number of scientific studies and new medical treatments. Last week I began a new one after one of my doctors suggested it as a way to help support my body’s ongoing healing.

I had my bilateral mastectomy in October 2020. When the pathology was done, the research team found that lymph nodes in my left breast were positive for cancer cells even though they had biopsied negative. Additionally, I had something called “vascular invasion” on my left side. This means a few pesky breast cancer cells were trying to make their way out of my breast tissue by traveling through my blood vessels and lymphatic system. I was fortunate that my surgery removed them and brought their journey to an end before they could do any more damage. We also did a second surgery under my left arm 2 weeks after my mastectomy to test those lymph nodes. Thankfully, all of the lymph nodes under my left arm were cancer-free (just like the ones under my right arm!) However, there was a very slight possibility that one or two of those cancer cells on the left side got away without us knowing. On the off chance that this happened, my radiation oncology team suggested radiation just on the left side to ensure we stopped them. (There was no vascular invasion on my right side, so radiation on the right side wasn’t needed.) Also, there was one lymph node very close to my lung and heart on the left side that was a tiny bit enlarged. Because of its location near my heart and lung, it was too risky to biopsy or remove it. So, radiation would be used to kill any cancer cells that might be trying to hang out in that lymph node.

In total, I had 6 weeks of radiation, 5 days each week, for a total of 30 radiation sessions. The last 5 sessions were a “boost” week meaning the radiation was stepped up to a higher level and aimed right at that lymph node near my heart and lung. Though I’m grateful for these lifesaving treatments, the side effects were a bit rough. I got a 3rd degree burn the size of a baseball in the center of my chest and it caused the muscles, ligaments, and tendons on the left side to tighten up considerably. Though I’ve regained almost all of my mobility in my upper body through a lot of hard work, those muscles, ligaments, and tendons on my left side are still very tight and my left shoulder rolls in very slightly as a result. This condition is called radiation fibrosis.

All of my medical cancer care is through NYU Langone Health in New York City. They recently hired Dr. Yingrong Zhu, a physiatrist who specializes in breast cancer survivorship. A physiatrist, also known as a physical medicine and rehabilitation (PM&R) physician, is a medical doctor specializing in diagnosing and treating conditions affecting the musculoskeletal system, nervous system, and other bodily functions, with the goal of restoring function and improving quality of life.

I went to see Dr. Zhu this week and had a fantastic experience. She explained that the effects of radiation can persist for 20 years – I had no idea! – so this issues I’m having with tightness deserve attention. She also explained that because I work out and stretch every day (including stretches given to me by my physical therapy team right after my active treatment), more physical therapy wasn’t likely to help me. However, she told me about some small scientific studies that show a 6-month course of vitamin E 1000 i.u. supplements combined with a medication called pentoxifylline ER can help release tension in muscles affected by radiation fibrosis and lead to increased mobility.

Together, Dr. Zhu and I decided it was worth me trying this new medication combo. The side effects are minimal, and she’s had a few other patients who have benefitted from it. It’s too soon to tell if it will help me, but I’m always willing to try anything that helps support my health and well-being. I also see this as an opportunity to not only help myself, but also to help others by sharing my experience with this new treatment. I’m excited about the possibility of regaining more of my mobility and improving my quality of life. Here’s hoping that someday I’ll be able to do my beloved yoga backbends again!

creativity

Lavender — soothing for the mind and saving the clean energy revolution

Christa Avampato
Lavender field in Provence, France. Photo by Antony BEC on Unsplash.

Soon, lavender’s scent won’t be the only reason it causes you to take a deep inhale. In addition to soothing your mind, it’s about to revolutionize the way we store clean energy.

Lithium-ion batteries are often used to store clean energy and power electric vehicles because they are cost-efficient and have a large storage capacity. However, they require lithium and cobalt, two elements that lead to mining operations that can pollute land and water, and often utilize child labor. Additionally, they’re difficult to recycle, often leading to landfill waste, and they require significant amounts of energy to produce.

Sodium-sulfur batteries are an alternative to lithium-ion batteries. Unlike lithium and cobalt, sodium and sulfur are abundant, easily obtained, and relatively easy to recycle. However, these batteries can’t store nearly as much energy as lithium-ion batteries, and their storage capacity is degraded even further after a few charging cycles. The challenge for scientists has been how to create a battery that has the benefits of lithium-ion batteries and sodium-sulfur batteries without the downsides of either. Lavender, or more specifically linalool, to the rescue!

Linalool is the compound responsible for lavender’s calming scent. (Linalool is also found in other plants such as basil, bay laurel, some cannabis strains, mint, cinnamon, citrus fruits, rosewood, guava, peach, plum, pineapple, and passionfruit.) A research team at the Max Planck Institute of Colloids and Interfaces led by Paolo Giusto found linalool interacts with sulfur to help sodium-sulfur batteries deliver more power and hold a better charge over hundreds of charging cycles.

“By taking a creative look at nature, we are finding solutions to many of the challenges posed by the energy transition, “ said Paolo Giusto.

Nature to the rescue, again. As a society, we need to recognize that nature is not something to by dominated by our egos, but rather a wider guide, teacher, and partner to help us improve the lives all beings while caring for the one planet we all share.

creativity

The many forms of medicine

Christa Avampato

Every day, I’m grateful for the gift to be here with all of you. As a cancer survivor, I’m alive because of science and modern medicine. In addition to those incredible resources, there are also many other forms of medicine that we can embrace to support our health and well-being.

Nature is medicine.
Fresh air is medicine.
Healthy food is medicine.
Water is medicine.
Movement is medicine.
Meditation is medicine.
Peace is medicine.
Joy is medicine.
Laughter is medicine.
Love is medicine.
Creativity is medicine.
Music is medicine.
Purpose is medicine.
Friendship is medicine.
Community is medicine.
A pet is medicine.
Freedom is medicine.
Time is medicine.
Travel is medicine.
Access to care is medicine.

creativity

Remembering 5 years ago today

Christa Avampato

5 years ago today, the world shut down because of COVID-19. While we still mourn what we lost, who we lost, and how things changed, I hope we also remember the compassion, care, community, and concern so many people exhibited for their neighbors. I hope we can remember those days now from where we are today, and say, “Look what we could do together.” I’m forever grateful to those on the frontlines who gave everything they had to do everything they could to protect all of us. We will never be able to thank them enough.

creativity

Destruction can be a new beginning

Christa Avampato
Redwood trees sprout from burned trees in Yosemite. Photo by Chris Daines. Creative Commons license. https://www.flickr.com/photos/staticantics/4966177427/

For most species, including humans, wildfires represent a dire threat. But against all odds, fire’s fast-moving flames, smoke-filled skies, and relentless heat don’t always signal death in nature. Some species have evolved extraordinary adaptations to turn destruction into an opportunity — a gateway to survival and even proliferation. Their stories reveal how nature’s resilience and ingenuity can flourish in the face of destruction, and how following their lead can help us do the same.

1. Pyrophilous (“fire-loving”) beetles

Commonly known as fire beetles, these species have infrared sensors that detect heat, and antennae receptors that detect smoke. Together, these sensors and receptors guide them to the fires from up to 80 miles away. But why would a beetle want to fly into the fire?

Scorched forests provide them with everything they need to help create the next generation — the intense heat lifts the bark from the tree trunks where the beetles lay their eggs; without competition from other insects and free from the threat of predators, the larvae have the decaying wood as an abundant food source.

These beetles also jump start the rewilding process after a fire to help rebuild the ecosystem. As they break down the decaying wood, they speed up the recycling of nutrients into the soil and accelerate the growth of new plants and trees.

How can we put the beetle’s adaptations to work for us? Studying the structure of their sensors and receptors could help engineers and designers develop tools to help us identify fires from long-range distances, allowing us to deploy fire fighters and resources earlier and more quickly to extinguish them sooner and more effectively. These beetles also teach us that within the ashes of destruction lie opportunities for something new to grow and begin the process of rebuilding.

2. Woodpeckers

Black-backed, red-cockaded, and white-headed woodpeckers see post-fire landscapes as tasty buffets. They feast on the beetle larvae abundant in these areas. The woodpeckers keep the beetle populations under control to balance the newly forming ecosystems recovering from wildfires. The open, grassland conditions that are present in the early stages of forest recovery are perfect places for woodpeckers to nest and forage for food.

Woodpeckers show us that places that don’t look perfect can often be perfect for our needs.

3. Redwood trees

After a fire, redwood trees sprout new seedlings. This process is known as epicormic sprouting. They store energy in dormant buds under their bark. Even after centuries, these buds can sprout. They also sprout new growth from the roots of burned trees. This ability to resprout from dormant buds and from their roots, even after the tree dies, gives redwoods an advantage over tree species that reproduce through seeds alone.

Redwoods developed this adaptation to prepare for difficult times, giving them the best chance of propagating the next generation, even if the trees themselves wouldn’t live to see that future themselves.

These three species are exemplars of how to survive and thrive through difficulties and disturbances. Right now, we’re facing multiple, painful challenges in our world. Feelings of hopelessness and helplessness are understandable. Life on Earth has existed for nearly 4 billion years, and nature has faced a constant barrage of challenges throughout and adapted. Beetles, woodpeckers, and redwoods are three examples of how to rise to and overcome challenges: always seek opportunity everywhere, even and especially in the places that don’t sparkle and shine; contribute and be part of the rebuilding community; in times of plenty, prepare for times of scarcity.

When the student is ready, the teacher will appear. Nature has the lessons we need to learn. We can benefit from nature’s nearly 4 billion years of accumulated wisdom if we are willing to put aside our own egos. Are we ready and willing to be nature’s students?

creativity

A reminder on where we can go from here

Christa Avampato
Photo by Holly Mandarich on Unsplash

Here’s a reminder I know I need every day, and maybe it will help you, too — At any age and stage in life, you can:

– Start over
– Start again
– Try something brand new
– Be a beginner
– Learn
– Grow
– Change
– Evolve
– Say goodbye
– Say hello
– Forgive
– Ask for forgiveness
– Pause
– Reflect
– Discover

You are allowed to do all those things, and many at the same time. You are never just one thing or one way. Who you’ve been, what you’ve done, and where you’ve been are prologue to who you will be, what you will do, and where you will go. The past is merely setting the scene and dressing the set for all the choices you will make and the adventures you will have that lie ahead.

creativity

NIH funding freeze endangers American lives and the US economy

Christa Avampato
Photo by National Cancer Institute on Unsplash. Chanelle Case Borden, Ph.D., a postdoctoral fellow in the National Cancer Institute’s Experimental Immunology Branch, pipetting DNA samples into a tube for polymerase chain reaction, or PCR, a laboratory technique used to make multiple copies of a segment of DNA.

Earlier this week, I wrote in my Togetherhood newsletter about the history and scientific research of Gila monster venom that led to Novo Nordicks’s medications Ozempic and Wegovy. This research began at the National Institutes of Health and led to some of the most profitable and promising drugs. These types of advances are now in danger because the Trump administration has frozen much of the $47 billion the US spends annually on biomedical research like this through 60,000 NIH grants.

The US houses the world’s leading medical labs that research cancer, dementia and Alzheimer’s, heart disease, child health, and diabetes to name just a few. NIH grants provide significant funding to these labs. To make sure the grants are used efficiently and ethically, there’s an extensive review process of grant applications. When the Trump administration froze the funding, they stopped all these review processes. These frozen funds also caused many research labs and universities that house them to halt hiring and PhD and post-doc admissions. Even if they released the funding today, it would take weeks or months to restart all these processes.

Additionally, freezing these funds is negatively impacting the economy and US competitiveness on the world stage. Every $1 of NIH spending generates more than $2 dollars in US economic activity. Healthcare is the biggest industry in the US. Without the foundation of NIH-funded research, the industry is in crisis. The US produces more influential health science research than the next 10 leading countries, combined. Every day that goes by, lives and livelihoods of Americans are in jeopardy. Please call your reps today and tell them to fight to restore NIH funding. Your life and the lives of those you love depend on it.

creativity

A monster created Ozempic

Christa Avampato
Gila monster. 2023. Photo by David Clode on Unsplash

If you’ve benefitted from the medications Ozempic, Wegovy, and others like them to treat diabetes and support weight management, thank the Gila monster. They have a hormone (exendin-4) that controls their blood sugar and delays the stomach from emptying, prolonging feelings of fullness. It’s similar in chemical composition to our GLP-1 hormone that performs the same functions in our bodies. However, the Gila monster’s exendin-4 allows them to stay healthy while eating only 5 to 10 times per year.

This ability to fast for long periods of time without impacting their health piqued the interest of endocrinologist Dr. John Eng and his team of researchers in the 1980s and 1990s. They set out to discover if a medication that mimics exendin-4 would help humans manage their blood sugar and weight.

A component of their venom, the Gila monster’s exendin-4 while similar to our GLP-1 was found by Eng and his team to be effective for much longer. In clinical trials, one injection of a medication inspired by exendin-4 helped diabetics keep their blood sugar under control for an entire week and decreased their appetite, helping them to lose weight, too.

Though it took decades of testing and evaluation, exenatide, a synthetic version of exendin-4 was approved by the FDA in 2005 to treat Type-2 diabetes. Research continued to evaluate it as a treatment for obesity and weight management. That research led the creation of semaglutide, the active ingredient in the drugs Ozempic and Wegovy.

Gila monsters are our elders. They trace their ancestry back to the Cretaceous period when dinosaurs ruled the planet, 145 – 66 million years ago, nearly 60 million years before our earliest ancestors made an appearance. Gila monsters are in essence “living fossils”. In that time, they evolved astounding abilities that we’re just beginning to fully understand.

Unfortunately, this creature who survived the catastrophic asteroid that wiped out the dinosaurs is steadily being wiped out by us. Their population is declining due to the pet trade and the destruction of habitat from agriculture and urbanization despite the fact that without them, the multi-billion-dollar drugs Ozempic, Wegovy, and others wouldn’t exist.

Nature, and the species with whom we share this one planet, are intricately tied to our health and well-being. Stories like that of the Gila monster and Ozempic remind us that nature is a research lab, pharmacy, archive, library, concert hall, and constant source of inspiration. When we threaten the lives of other species, we compromise our own opportunities to live well. There’s no getting around it: We are a part of nature, not apart from nature. How bright our future will be depends on how much we respect and safeguard the natural world, and the health of the ecosystems within which we all live.

creativity

You’re safe with me

Christa Avampato

There are a lot of people in the U.S. who don’t know who they’re safe with right now. I want to say this loudly and publicly: if you’re a good, decent person who works hard, and cares about other beings and this beautiful planet we all share, you’re safe with me. You’re welcome at my table. Come as you are, be as you are. As long as we don’t give up, it’s not over. They are counting on us giving up. And there’s no way I’m ever giving up. There’s too much at stake. I’m in this with you. I got you.

creativity

Introducing my bloodhound foster puppies, Sophia and Dorothy

Christa Avampato
Dorothy (left) and Sophia (right)

Let me tell you a story. Picture it. Sicily, 1922… Seriously, though the story of these 2 babies and their sisters, Rose and Blanche, is a doozy.

In Queens, a member of the Muddy Paws Rescue community observed horrid conditions of backyard breeders. Their adult male and female bloodhounds had a litter of 4 puppies in mid-December. The parents and puppies were left outside, in all weather conditions, with no shelter and not enough food. Muddy Paws offered resources to have the adult dogs altered. The people refused that help though they did agree to give her the puppies so we could find homes for them. (I’m going to find out what can be done to help the adult dogs who are still with those people. More on that later…)

Despite their difficult start, Sophia and Dorothy are incredible dogs. They don’t show any signs of trauma. They are floppy, happy, energetic, gorgeous puppies. They love each other, share everything, and are either wrestling, eating, or napping on top of each other. That they’re even alive is amazing. That they’re alive, completely healthy, and well-adjusted is a miracle. They’ll need training of course, as all dogs do, and I can’t wait to see them shine in their new forever homes whenever they get adopted.

Right now, they’re indoor only puppies until they get all of their vaccines. They’ve been keeping me busy as we figure out how to set up my apartment and get into a routine. I think we’re doing pretty well considering I’ve never had puppies this young and never had 2 dogs at once. I haven’t looked much at the news, which has been a welcome reprieve, and they’ve brought me so much joy and laughter.

Today I sent their photos and wrote their profiles for their adoption pages that will be on the Muddy Paws Rescue website this week. They’ll be at the adoption event this coming Saturday, February 22nd. No matter how long I end up having them – whether it’s 1 week or many weeks – I’ll be forever grateful to them for showing me that how we start is just that. It’s only a beginning. Those we meet along our path can change everything.